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Home > Probiotics > PS128™

Probiotics for Neurological & Mental Health 

Lactiplantibacillus plantarum PS128™ is classified as a psychobiotic that has the unique potential to modulate neurotransmitters (dopamine and serotonin), the stress hormone (cortisol), and more. PS128™ bridges the gap between ordinary probiotics and pharmaceuticals, with robust clinical data concerning Parkinson’s disease (PD), clinical depression, anxiety, autism spectrum disorder (ASD), and even athletic endurance performance.

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What are the benefits of PS128™?

The main psychological benefits of PS128™ come from regulating dopamine and serotonin, and reducing cortisol throughout the body. PS128™ also boosts key short chain fatty acids that are essential for healthy metabolism.

 

PS128™ has both antioxidant and anti-inflammatory properties to help protect your body from toxins found in food and the environment. 

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What do studies say about PS128™?

PS128™ probiotic for neurological health is registered in 40 countries worldwide, has been tested in 14 clinical studies, and has led to 26 registered patents.

 

Studies found that taking PS128™ improved symptoms in 68% of patients with neurodegenerative disorders, such as Parkinson’s disease, and 87% of patients with neurodevelopmental disorders, such as ASD.

Why are probiotics important for a healthy body & mind?

Our gut microbes are essential to the two-way connection between our enteric (intestinal) and central nervous systems.

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This relationship is called our “microbiota-gut-brain-axis.” Probiotics work with our gut microbes, the food we consume, neurons, endocrine cells, and various immune receptors. They produce short chain fatty acids (SCFAs), balance neurotransmitter and hormone levels, modify genetic expression within our cells, and promote many other health benefits.

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How does PS128™ work? 

From within the gut, PS128™ regulates multiple pathways that determine concentrations of different molecules in the body. Its main mechanism of action is still being studied, but we know PS128™ has the unique potential to modulate neurotransmitters (dopamine and serotonin), the stress hormone (cortisol), and more.

 

An imbalance in any of these molecules can cause symptoms and disorders that may be benefited by taking PS128™.

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What are the key functions & benefits of PS128™?

PS128™ offers 14 main functions and benefits in regular use as part of a healthy diet:

  • Improves post-workout physical recovery

  • ​​Promotes healthy digestion as foundation of gut-brain axis

  • Proven safety: GRAS (USA), QPS (EU)

  • Proven evidence for significant improvement of central nervous system conditions

  • Effective for neurodevelopmental and neurodegenerative disorders

  • Effective for depression and insomnia

  • Vegan, Kosher & Halal

  • Shelf stable

  • Regulates dopamine for motor control & motivation

  • Regulates serotonin for mood & sleep

  • Reduces stress-related cortisol levels throughout the body

  • Increases amounts of key short-chain fatty acids (SCFAs)

  • Has antioxidant and anti-inflammatory properties – reduces TNF-α and IL-6, and increases IL-10

  • Improves athletic endurance

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